U.S. FEDRegulation
EPA issues significant new use rules for 19 chemical substances under TSCA
The Environmental Protection Agency issued final significant new use rules under section 5(a)(2) of the Toxic Substances Control Act for 19 chemical substances that were subject to premanufacture notices and section 5(e) orders. The rules, published October 15, 2026, at 91 FR 65461 in 40 CFR part 721, take effect December 14, 2026, under Docket No. EPA-HQ-OPPT-2026-0499.
Key points
- Persons must notify EPA at least 90 days before manufacturing or processing a listed substance for a designated significant new use.Federal Register
- Manufacture or processing for the significant new use must not commence until EPA completes its review and determination.Federal Register
- The rules add 40 CFR 721.12260 through 721.12278 and carry RIN 2070-AB27.Federal Register
- Importers remain subject to TSCA section 13 import certification and exporters to section 12(b) export notification.Federal Register
- The rule is FR Doc. 2026-21051; the substances were the subject of premanufacture notices and TSCA section 5(e) orders.Federal Register
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Federal Register
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RegulationU.S.Significant New Use Rules on Certain Chemical Substances (26-1)EnvironmentalRegulatoryFor practitionersFor governance