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U.S. FEDRegulation

DEA places diphenidine in Schedule I of the Controlled Substances Act

The Drug Enforcement Administration placed diphenidine (1-(1,2-diphenylethyl)piperidine), including its salts, isomers, and salts of isomers, in Schedule I of the Controlled Substances Act by final rule published September 21, 2026 (91 FR 59695, FR Doc. 2026-19231), effective October 21, 2026. Anyone who manufactures, distributes, imports, exports, researches or possesses the substance becomes subject to Schedule I registration, security and recordkeeping requirements and to administrative, civil and criminal sanctions. The rule implements US obligations under the 1971 Convention on Psychotropic Substances.

Text (Federal Register) →

Key points

  • Diphenidine, including its salts, isomers, and salts of isomers, is placed in Schedule I of the Controlled Substances Act.Federal Register
  • Anyone manufacturing, distributing, importing, exporting, researching, analysing or possessing diphenidine faces Schedule I registration, security and recordkeeping duties.Federal Register
  • The scheduling is effective October 21, 2026.Federal Register
  • The action implements United States obligations under the 1971 Convention on Psychotropic Substances.Federal Register
  • The final rule is published at 91 FR 59695 (FR Doc. 2026-19231).Federal Register

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RegulationU.S.DEA: Placement of Diphenidine in Schedule IRegulatoryFor practitionersFor governance